Skip to main content

New high rank publication in Nature Nanotechnology

We are pleased to anounce a new publication in Nature Nanotechnology titeled "Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens" by Dominik Kylies and Victor Puelles (project A9).


Kylies and Puelles give a detailled report on expansion-enhanced super resolution radial fluctuations (ExSRRF) as a simple yet powerful workflow for providing a resolution of up to 25 nm using LED-based widefield microscopy. Beside enableing molecular profiling of subcellular structures in FFPE sections, Kylies and Puelles showed a potential application in clinical pathology by identifying and quantifying classical features of endoplasmic reticulum stress in murine model as well as diagnositc ultrastructural features in human kidney biopsies.
Nature Nanotechnology. 2023 Apr