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6th August – New Publications

We are glad to announce new publications for this month. The research group of Prof. Steinmetz and Dr. Kluger (Project A3) got a new paper accepted by the Journal of the American Society of Nephrology.

"A Novel Role for IL-6 Receptor Classic Signaling: Induction of RORγt+Foxp3+ Tregs with Enhanced Suppressive Capacity."
Hagenstein J, Melderis S, Nosko A, Warkotsch MT, Richter JV, Ramcke T, Herrnstadt GR, Scheller J, Yan I, Mittrücker HW, Kluger MA, Steinmetz OM.
J Am Soc Nephrol.
2019 Aug;30(8):1439-1453. doi: 10.1681/ASN.2019020118.

Two editorials in JASN as well as Nature Reviews Nephrology will complement the publication:

  • The Complex Role of Interleukin 6 in Regulating T-cell Responses during Acute Glomerulonephritis. Cormican S, Griffin MD. J Am Soc Nephrol. 2019 Aug;30(8):1341-1344.
  • IL-6-dependent regulatory T cells in GN. Wang, M. Nat Rev Nephrol, https://doi.org/10.1038/s41581-019-0193-9

Furthermore, an article from the research group of Meyer-Schwesinger (Project B3) got accepted by the Journal of Immunology. Additionally, a publication with SFB-affiliation of Project A5 got published in Cell Reports.

"Deubiquitinating enzyme UCH-L1 promotes dendritic cell antigen cross presentation by favoring recycling of MHC I molecules"
Anna T. Reinicke, Friederike Raczkowski, Malte Mühlig, Pina Schmucker, Timo Lischke, Julia Reichelt, Enja Schneider, Stephanie Zielinski, Marlies Sachs, Elisabeth Jurack, Eva Tolosa, Christian Kurts, Hans-Willi Mittrücker and Catherine Meyer-Schwesinger

"Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells."
Likai Tan, Inga Sandrock, Ivan Odak, Yuval Aizenbud, Anneke Wilharm, Joana Barros-Martins, Yaara Tabib, Alina Borchers, Tiago Amado, Lahiru Gangoda, Marco J. Herold, Marc Schmidt-Supprian, Jan Kisielow, Bruno Silva-Santos, Christian Koenecke, Avi-Hai Hovav, Christian Krebs, Immo Prinz, Sarina Ravens
Cell Rep. 2019 Jun 18;27(12):3657-3671.e4. doi: 10.1016/j.celrep.2019.05.064.

We congratulate all involved contributors!