Publikationen 2023
The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis.
Georg R Herrnstadt, Christoph B Niehus, Torben Ramcke , Julia Hagenstein, Laura-Isabell Ehnold, Anna Nosko, Matthias T Warkotsch, Frederic C Feindt, Simon Melderis, Hans-Joachim Paust, Varshi Sivayoganathan, Saskia-Larissa Jauch-Speer, Milagros N Wong, Daniela Indenbirken, Christian F Krebs, Tobias B Huber, Ulf Panzer, Victor G Puelles, Malte A Kluger, Oliver M Steinmetz.
Kidney Int. 2023 Mar
CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.
Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O Wenzel, Oliver M Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T Lindenmeyer, Elion Hoxha, Rolf A K Stahl, Tobias B Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F Krebs, Ulf Panzer
Sci Transl Med. 2023 Mar
Pathogenicity of Human Anti-PLA 2 R1 Antibodies in Minipigs: A Pilot Study.
Linda Reinhard, Thorsten Wiech, Aline Reitmeier, Moritz Lassé, Maya Machalitza, Asmus Heumann, Nicoletta Ferru, Desiree Loreth, Marie-Luise Schröder, Arvid Hutzfeldt, Felix R Stahl, Sven Peine, Hermann-Josef Gröne, Catherine Meyer-Schwesinger, Markus M Rinschen, Rolf A K Stahl, Elion Hoxha
J Am Soc Nephrol. 2023 Mar
False positivity for PLA2R1 antibody measured by ELISA in a nephrotic patient with no membranous nephropathy.
Elion Hoxha, Linda Reinhard, Thomas Castedello, Jan U Becker
Kidney Int. 2023 Feb
The classical pathway triggers pathogenic complement activation in membranous nephropathy.
Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger, Naemi Hickstein, Silke Dehde, Sonia Wulf, Sarah M S Köllner, Renke Lucas, Dominik Kylies, Sarah Froembling, Stephanie Zielinski, Oliver Kretz, Anna Borodovsky, Sergey Biniaminov, Yanyan Wang, Hong Cheng, Friedrich Koch-Nolte, Peter F Zipfel, Helmut Hopfer, Victor G Puelles, Ulf Panzer, Tobias B Huber, Thorsten Wiech, Nicola M Tomas
Nat Commun. 2023 Jan
Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury.
Jan-Hendrik Riedel, Lennart Robben, Hans-Joachim Paust, Yu Zhao, Nariaki Asada, Ning Song, Anett Peters, Anna Kaffke, Alina Borchers, Gisa Tiegs, Larissa Seifert, Nicola M Tomas, Elion Hoxha, Ulrich O Wenzel, Tobias B Huber, Thorsten Wiech, Jan-Eric Turner, Christian F Krebs, Ulf Panzer
JCI Insight. 2023 Jan
Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram T, Reimers D, Lory NC, Schmidt C, Schmid J, C Heinig L, Bradtke P, Rattay G, Zielinski S, Hellmig M, Bartsch P, Rohde H, Nuñez S, Rosemblatt MV, Bono MR, Gagliani N, Sandrock I, Panzer U, Krebs CF, Meyer-Schwesinger C, Prinz I, Mittrücker HW
Proc Natl Acad Sci U S A. 2023 Jan