Publications
Kidney dendritic cells: fundamental biology and functional roles in health and disease.
Kurts C, Ginhoux F, Panzer U
Nat Rev Nephrol. 2020 Jul
A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier.
Liang W, Yamahara K, Hernando-Erhard C, Lagies S, Wanner N, Liang H, Schell C, Kammerer B, Huber TB, Bork T.
Kidney Int. 2020 Jun
Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells.
Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC.
Cell. 2020 May
Multi-organ and renal tropism of SARS-CoV-2
Puelles VG, Lütgehetmann M, Lindenmeyer MT, Sperhake JP, Wong MN, Allweiss L, Chilla S, Heinemann A, Nicola Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder AS, Edler C, Gross O, Glatzel M, Wichmann D, Wiech T, Stefan Kluge S, Pueschel K, Aepfelbacher M, Huber TB
New England Journal of Medicine. 2020 May
Drawing a single-cell landscape of the human kidney in (pseudo)-space and time.
Krebs CF, Schlitzer A, Kurts C.
Kidney Int. 2020 May
COVID-19-associated nephritis: early warning for disease severity and complications?
Gross O, Moerer O, Weber M, Huber TB, Scheithauer S
The Lancet. Published Online 2020 May
TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer.
Laura Garcia Perez, Jan Kempski, Heather M McGee, Penelope Pelzcar, Theodora Agalioti, Anastasios Giannou, Leonie Konczalla, Leonie Brockmann, Ramez Wahib, Hao Xu, Maria Carolina Amezcua Vesely, Shiwa Soukou, Babett Steglich, Tanja Bedke, Carolin Manthey, Oliver Seiz, Björn-Philipp Diercks, Stylianos Gnafakis, Andreas H Guse, Daniel Perez, Jakob R Izbicki, Nicola Gagliani, Richard A Flavell, Samuel Huber
Nat Commun. 2020 May
A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients
Meyer-Schwesinger C*, Tomas NM*, Dehde S, Seifert L, Hermans-Borgmeyer I, Wiech T, Koch-Nolte F, Huber TB, Zahner G.
Kidney Int. 2020 May
* contributed equally
A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients.
Catherine Meyer-Schwesinger, Nicola M Tomas, Silke Dehde, Larissa Seifert, Irm Hermans-Borgmeyer, Thorsten Wiech, Friedrich Koch-Nolte, Tobias B Huber, Gunther Zahner
Kidney Int. 2020 May
B6.Rag1 Knockout Mice Generated at the Jackson Laboratory in 2009 Show a Robust Wild-Type Hypertensive Phenotype in Response to Ang II (Angiotensin II).
Seniuk A, Thiele JL, Stubbe A, Oser P, Rosendahl A, Bode M, Meyer-Schwesinger C, Wenzel UO, Ehmke H.
Hypertension. 2020 Apr
A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation.
Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C
Sci Transl Med. 2020 Mar
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis.
Jingyuan Xie, Lili Liu, Nikol Mladkova, [...] Elion Hoxha, Rolf A K Stahl, [...] Robert Kleta, Nan Chen, Krzysztof Kiryluk
Nat Commun. 2020 Mar
Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis.
Koehler S, Kuczkowski A, Kuehne L, Jüngst C, Hoehne M, Grahammer F, Eddy S, Kretzler M, Beck BB, Höhfeld J, Schermer B, Benzing T, Brinkkoetter PT, Rinschen MM.
J Am Soc Nephrol. 2020 Mar
CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.
Zipfel PF, Wiech T, Stea ED, Skerka C.
J Am Soc Nephrol. 2020 Feb
Cellular and Molecular Probing of Intact Human Organs.
Zhao S, Todorov MI, Cai R, -Maskari RA, Steinke H, Kemter E, Mai H, Rong Z, Warmer M, Stanic K, Schoppe O, Paetzold JC, Gesierich B, Wong MN, Huber TB, Duering M, Bruns OT, Menze B, Lipfert J, Puelles VG, Wolf E, Bechmann I, Ertürk A.
Cell. 2020 Feb
Renal clearance of polymeric nanoparticles by mimicry of glycan surface of viruses.
Wyss PP, Lamichhane SP, Abed A, Vonwil D, Kretz O, Huber TB, Sarem M, Shastri VP.
Biomaterials. 2020 Feb
Innate Lymphoid Cells in Renal Inflammation.
Becker M, Gnirck AC, Turner JE
Front Immunol. 2020 Jan
Clinical Relevance of Domain-Specific Phospholipase A2 Receptor 1 Antibody Levels in Patients with Membranous Nephropathy.
Linda Reinhard, Gunther Zahner, Stephan Menzel, Friedrich Koch-Nolt, Rolf A K Stahl, Elion Hoxha
J Am Soc Nephrol. 2020 Jan
Podocytes maintain high basal levels of autophagy independent of mtor signaling.
Bork T, Liang W, Yamahara K, Lee P, Tian Z, Liu S, Schell C, Thedieck K, Hartleben B, Patel K, Tharaux PL, Lenoir O, Huber TB.
Autophagy. 2019 Dec
Primary decidual zone formation requires Scribble for pregnancy success in mice.
Yuan J, Aikawa S, Deng W, Bartos A, Walz G, Grahammer F, Huber TB, Sun X, Dey SK.
Nat Commun. 2019 Nov