The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension. 

Weiss S, Rosendahl A, Czesla D, Meyer-Schwesinger C, Stahl RA, Ehmke H, Kurts C, Zipfel PF, Köhl J, Wenzel UO
Am J Physiol Renal Physiol. 2016 Jun