Publikationen

2018
Molecular and functional heterogeneity of IL-10-producing CD4+ T cells

Brockmann L, Soukou S, Steglich B, Czarnewski P, Zhao L, Wende S, Bedke T, Ergen C, Manthey C, Agalioti T, Geffken M, Seiz O, Parigi S, Sorini C, Geginat J, Fujio K, Jacobs T, Roesch T, Izbicki J, Lohse A, Flavell R, Krebs C, Gustafsson J, Antonson P, Roncarolo M, Villablanca E, Gagliani N, Huber S
Nat Commun. 2018 Dec 21;9(1):5457. doi: 10.1038/s41467-018-07581-4.
https://www.ncbi.nlm.nih.gov/pubmed/30575716
A5
Huber S., Krebs

Antigen-Specific IgG Subclasses in Primary and Malignancy-Associated Membranous Nephropathy.

von Haxthausen F, Reinhard L, Pinnschmidt HO, Rink M, Soave A, Hoxha E, Stahl RAK
Front Immunol. 2018 Dec 20;9:3035. doi: 10.3389/fimmu.2018.03035. eCollection 2018.
https://www.ncbi.nlm.nih.gov/pubmed/30619370
B1
Von Haxthausen, Stahl, Reinhard, Hoxha

Development and validation of a renal risk score in ANCA-associated glomerulonephritis

Brix S, Noriega M, Tennstedt P, Vettorazzi E, Busch M, Nitschke M, Jabs W, Özcan F, Wendt R, Hausberg M, Sellin L, Panzer U, Huber T, Waldherr R, Hopfer H, Stahl R, Wiech T

Kidney Int.2018 Dec;94(6):1177-1188. doi: 10.1016/j.kint.2018.07.020. Epub 2018 Oct 29.
https://www.ncbi.nlm.nih.gov/pubmed/30385041
B6
Wiech, Panzer, Huber, Stahl

Bevacizumab-associated glomerular microangiopathy

Person F, Rinschen M, Brix S, Wulf S, Noriega M, Fehrle W, Schmitz J, Schwarz A, Ivanyi P, Steinmetz O, Reinhard L, Hoxha E, Zipfel P, Bräsen J, Wiech T
Mod Pathol. 2018 Dec 14. doi: 10.1038/s41379-018-0186-4. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/30552416
B6
Wiech, Steinmetz, Reinhard, Hoxha, Zipfel

”Adaptive immunity and IL-17A are not involved in the progression of chronic kidney disease after 5/6 nephrectomy in mice.”

Rosendahl A, Kabiri R, Bode M, Cai A, Klinge S, Ehmke H, Mittrücker HW, Wenzel UO

Br J Pharmacol. 2018 Sep 30. doi: 10.1111/bph.14509. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/30270435
B7
Bode, Klinge, Ehmke, Mittrücker, Wenzel

 

The chemokine receptor CX3CR1 reduces renal injury in mice with angiotensin II induced hypertension

Ahadzadeh E, Rosendahl A, Czesla D, Steffens P, Prüßner L, Meyer-Schwesinger C, Wanner N, Paust H, Huber T, Stahl R, Wiech T, Kurts C, Seniuk A, Ehmke H, Wenzel U

Am J Physiol Renal Physiol. 2018 Sep 12. doi: 10.1152/ajprenal.00149.2018. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/30207169
B7
Meyer-Schwesinger, Paust, Huber T, Stahl, Wiech, Kurts, Ehmke, Wenzel

T cell-derived IFN-γ downregulates protective group 2 innate lymphoid cells in murine lupus erythematosus. 

Düster M, Becker M, Gnirck AC, Wunderlich M, Panzer U, Turner JE

Eur J Immunol. 2018 Aug;48(8):1364-1375. doi: 10.1002/eji.201747303. Epub 2018 May 17.

https://www.ncbi.nlm.nih.gov/pubmed/29671873

A6

Turner, Gnirck, Panzer

Organisation of lymphocytic infiltrates in ANCA-associated glomerulonephritis

Brix S, Noriega M, Herden E, Goldmann B, Langbehn U, Busch M, Jabs W, Steinmetz O, Panzer U, Huber T, Stahl R, Wiech T
Histopathology. 2018 Jun;72(7):1093-1101. doi: 10.1111/his.13487. Epub 2018 Mar 25.

https://www.ncbi.nlm.nih.gov/pubmed/29453894

B6

Wiech, Steinmetz, Panzer, Huber T, Stahl

IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN. 

Diefenhardt P, Nosko A, Kluger MA, Richter JV, Wegscheid C, Kobayashi Y, Tiegs G, Huber S, Flavell RA, Stahl RAK, Steinmetz OM

J Am Soc Nephrol. 2018 Jun 4. pii: ASN.2017091044. doi: 10.1681/ASN.2017091044. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29866800

A3

Steinmetz, Kluger, Tiegs, Huber S. Stahl

 
The Most N-Terminal Region of THSD7A Is the Predominant Target for Autoimmunity in THSD7A-Associated Membranous Nephropathy.
Seifert L, Hoxha E, Eichhoff AM, Zahner G, Dehde S, Reinhard L, Koch-Nolte F, Stahl RAK, Tomas NM

J Am Soc Nephrol. 2018 May;29(5):1536-1548. doi: 10.1681/ASN.2017070805. Epub 2018 Mar 19.

https://www.ncbi.nlm.nih.gov/pubmed/29555830

B2
Seifert; Hoxha; Zahner, Reinhard, Koch-Nolte, Stahl, Tomas
 
 
IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation. 
Krohn S, Nies JF, Kapffer S, Schmidt T, Riedel JH, Kaffke A, Peters A, Borchers A, Steinmetz OM, Krebs CF, Turner JE, Brix SR, Paust HJ, Stahl RAK, Panzer U

J Am Soc Nephrol. 2018 Apr;29(4):1210-1222. doi: 10.1681/ASN.2017090949. Epub 2018 Feb 26.

https://www.ncbi.nlm.nih.gov/pubmed/29483158

A1
Panzer; Hiekmann (geb. Krohn), Kapffer, Schmidt, Riedel, Steinemtz, Krebs, Turner, Paust, Stahl
 
FHR5 Binds to Laminins, Uses Separate C3b and Surface-Binding Sites, and Activates Complement on Malondialdehyde-Acetaldehyde Surfaces.
Rudnick RB, Chen Q, Stea ED, Hartmann A, Papac-Milicevic N, Person F, Wiesener M, Binder CJ, Wiech T, Skerka C, Zipfel PF

J Immunol. 2018 Apr 1;200(7):2280-2290. doi: 10.4049/jimmunol.1701641. Epub 2018 Feb 26.

 https://www.ncbi.nlm.nih.gov/pubmed/29483359

B6

Wiech; Zipfel

Immunohistochemical and serological characterization of membranous nephropathy in children and adolescents
Dettmar A, Wiech T, Kemper M, Soave A, Rink M, Oh J, Stahl R, Hoxha E
Pediatr Nephrol. 2018 Mar;33(3):463-472. doi: 10.1007/s00467-017-3817-y. Epub 2017 Oct 15.
https://www.ncbi.nlm.nih.gov/pubmed/29034405
B1
Hoxha, Stahl, Oh, Dettmar, Wiech

Ubiquitin C-Terminal Hydrolase L1 is required for regulated protein degradation through the ubiquitin proteasome system in kidney
Radón V, Czesla M, Reichelt J, Fehlert J, Hammel A, Rosendahl A, Knop J, Wiech T, Wenzel U, Sachs M, Reinicke A, Stahl R, Meyer-Schwesinger C

Kidney Int. 2018 Jan;93(1):110-127. doi: 10.1016/j.kint.2017.05.016. Epub 2017 Jul 26.

https://www.ncbi.nlm.nih.gov/pubmed/28754552

B3

Meyer-Schwesinger, Wiech, Wenzel, Sachs M, Stahl

Review & Editorials & Case Reports

"Protecting the kidney against autoimmunity and inflammation."

Christian Kurts, Catherine Meyer-Schwesinger

Nat Rev Nephrol. 2018 Dec 17. doi: 10.1038/s41581-018-0097-0. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30559368

B3 und A8

Meyer-Schwesinger und Kurts

Potential role for urine PCR in the diagnosis of Whipple's disease. Moter A,

Moter AJanneck MWolters MIking-Konert CWiessner ALoddenkemper CHartleben BLütgehetmann MSchmidt JLangbehn UJanssen SGeelhaar-Karsch ASchneider TMoos VRohde HKikhney JWiech T.

Clin Infect Dis. 2018 Oct 22. doi: 10.1093/cid/ciy664. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30351371

B6

Wiech

Lupusnephritis
Melderis S, Wiech T, Iking-Konert C, Steinmetz O

Z Rheumatol. 2018 Sep;77(7):593-608. doi: 10.1007/s00393-018-0496-4.

https://www.ncbi.nlm.nih.gov/pubmed/29955955

A3 / B6

Melderis; Wiech; Steinmetz

Innate Lymphoid Cells – Key players in tissue-specific immunity. 

Turner JE, Gasteiger G

Semin Immunopathol. 2018 Jul;40(4):315-317. doi: 10.1007/s00281-018-0690-0. Epub 2018 Jun 27

https://www.ncbi.nlm.nih.gov/pubmed/29951905

A6

Turner

Innate lymphoid cells in autoimmunity and chronic inflammatory diseases. 

Xiong T, Turner JE
Semin Immunopathol. 2018 Jul;40(4):393-406. doi: 10.1007/s00281-018-0670-4. Epub 2018 Mar 22.
https://www.ncbi.nlm.nih.gov/pubmed/29568972
A6
Xiong; Turner

Salt, inflammation, IL-17 and hypertension.

Wenzel UO, Bode M, Kurts C, Ehmke H.
Br J Pharmacol. 2018 May 16. doi: 10.1111/bph.14359. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29767465
B6
Wenzel, Bode, Kurts, Ehmke

III. Medizinische Klinik und Poliklinik
Universitätsklinikum Hamburg-Eppendorf

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